Photocatalyzed generation and application of sulfoximidoyl radicals

Zhang, Duo; Bolm, Carsten (Thesis advisor); Albrecht, Markus (Thesis advisor)

Aachen (2019)
Dissertation / PhD Thesis

Dissertation, RWTH Aachen University, 2019


To date, nitrogen-centered radicals (NCRs) and sulfur(VI)-centered radicals have received increasing attention as a class of appealing intermediates in synthetic methods. Over recent years, a series of methods have been used to generate NCRs and sulfur(VI)-centered radicals, such as visible light photocatalysis, metal catalysis, and thermolysis. Based on the previous studies, we know that the research of NCRs and sulfur(VI)-centered radicals can promote the development of synthetic strategies and medicinal chemistry. Design and application of novel nitrogen-centered radical and sulfur(VI)-centered radical precursors in the reactions to afford new NCRs and sulfur(VI)-centered radicals are becoming more and more important. In those projects, sulfoximine-based compounds were synthesized and used to afford the new NCRs and sulfur(VI)-centered sulfoximidoyl radicals in the photocatalytic reactions.